In vitro methylation of specific regions of the cloned Moloney sarcoma virus genome inhibits its transforming activity.

The transforming activity of cloned Moloney sarcoma virus (MSV) proviral DNA was inhibited by in vitro methylation of the DNA at cytosine residues, using HpaII and HhaI methylases before transfection into NIH 3T3 cells. The inhibition of transforming activity due to HpaII methylation was reversed by...

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Bibliografski detalji

Izdano u:	Mol Cell Biol
Glavni autori:	McGeady, M L, Jhappan, C, Ascione, R, Vande Woude, G F
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 1983
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368539/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6843547/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.3.305-314.1983
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