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DNA damage induced by oridonin involves cell cycle arrest at G2/M phase in human MCF-7 cells

AIM OF THE STUDY: To study the mechanisms of inhibition of cell growth and induction of DNA damage in oridonin-treated MCF-7 human breast cancer cells. MATERIAL AND METHODS: The cytotoxicity of oridonin-treated MCF-7 cells was measured by MTT assay. Cell cycle phase distribution was analyzed by flow...

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Detalhes bibliográficos
Main Authors: Zhang, Tao, Tan, Yan, Zhao, Rui, Liu, Zhaoyang
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685353/
https://ncbi.nlm.nih.gov/pubmed/23788960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/wo.2013.33772
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