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Improving Escherichia coli FucO for Furfural Tolerance by Saturation Mutagenesis of Individual Amino Acid Positions

Furfural is an inhibitory side product formed during the depolymerization of hemicellulose with mineral acids. In Escherichia coli, furfural tolerance can be increased by expressing the native fucO gene (encoding lactaldehyde oxidoreductase). This enzyme also catalyzes the NADH-dependent reduction o...

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Autors principals: Zheng, Huabao, Wang, Xuan, Yomano, Lorraine P., Geddes, Ryan D., Shanmugam, Keelnatham T., Ingram, Lonnie O.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685246/
https://ncbi.nlm.nih.gov/pubmed/23475621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00149-13
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