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Improving Escherichia coli FucO for Furfural Tolerance by Saturation Mutagenesis of Individual Amino Acid Positions

Furfural is an inhibitory side product formed during the depolymerization of hemicellulose with mineral acids. In Escherichia coli, furfural tolerance can be increased by expressing the native fucO gene (encoding lactaldehyde oxidoreductase). This enzyme also catalyzes the NADH-dependent reduction o...

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Detalhes bibliográficos
Main Authors: Zheng, Huabao, Wang, Xuan, Yomano, Lorraine P., Geddes, Ryan D., Shanmugam, Keelnatham T., Ingram, Lonnie O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685246/
https://ncbi.nlm.nih.gov/pubmed/23475621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00149-13
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