Comparison of Modeling Methods to Determine Liver-to-blood Inocula and Parasite Multiplication Rates During Controlled Human Malaria Infection

Controlled human malaria infection is used to measure efficacy of candidate malaria vaccines before field studies are undertaken. Mathematical modeling using data from quantitative polymerase chain reaction (qPCR) parasitemia monitoring can discriminate between vaccine effects on the parasite's...

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Detalhes bibliográficos
Main Authors: Douglas, Alexander D., Edwards, Nick J., Duncan, Christopher J. A., Thompson, Fiona M., Sheehy, Susanne H., O'Hara, Geraldine A., Anagnostou, Nicholas, Walther, Michael, Webster, Daniel P., Dunachie, Susanna J., Porter, David W., Andrews, Laura, Gilbert, Sarah C., Draper, Simon J., Hill, Adrian V. S., Bejon, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685228/
https://ncbi.nlm.nih.gov/pubmed/23570846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit156
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