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Maintenance of protein synthesis in spite of mRNA breakdown in interferon-treated HeLa cells infected with reovirus.

Interferon induces the synthesis of an enzyme which synthesizes 2',5'-oligoadenylate [2',5'-oligo(A)] when activated by double-stranded RNA. The 2',5'-oligo(A) in turn activates an endonuclease (RNase L). Concentrations of 2',5'-oligo(A) sufficient to activate RNase L are formed in interferon-treate...

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Udgivet i:Mol Cell Biol
Principais autores: Nilsen, T W, Maroney, P A, Baglioni, C
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368503/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6828030/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.3.1.64-69.1983
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