Interferon action: binding of viral RNA to the 40-kilodalton 2'-5'-oligoadenylate synthetase in interferon-treated HeLa cells infected with encephalomyocarditis virus.

The 40-kDa 2'-5'-oligoadenylate [(2'-5') (A)n] synthetase isoenzyme was proven to be a mediator of the inhibition of encephalomyocarditis virus (EMCV) replication by interferon (IFN). When activated by double-stranded RNA, this enzyme converts ATP into 2'-5'-oligoadenylate [(2'-5') (A)n], and (2'-5'...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Gribaudo, G, Lembo, D, Cavallo, G, Landolfo, S, Lengyel, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239981/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705989/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.4.1748-1757.1991
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