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Sex differences in behavioral and neural cross-sensitization and escalated cocaine taking as a result of episodic social defeat stress in rats

RATIONALE: Episodic social defeat stress results in cross-sensitization to cocaine, characterized by augmentation of locomotor activation, dopamine (DA) levels in the nucleus accumbens (NAc), and cocaine self-administration during a 24-hour “binge” in male rats. However, females are more vulnerable...

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Main Authors: Holly, Elizabeth N., Shimamoto, Akiko, DeBold, Joseph F., Miczek, Klaus A.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684960/
https://ncbi.nlm.nih.gov/pubmed/22926005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2846-2
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