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Poly (ADP-Ribose) Polymerase Inhibitor MK-4827 together with Radiation as a Novel Therapy for Metastatic Neuroblastoma

BACKGROUND/AIM: To assess poly (ADP-ribose) polymerase (PARP) inhibitor MK-4827 together with radiation for the treatment of neuroblastoma. MATERIAL AND METHODS: Clonogenic survival assays were used to assess MK-4827, radiation and combination thereof in four neuroblastoma cell lines. In vivo effica...

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Detalhes bibliográficos
Main Authors: Mueller, Sabine, Bhargava, Samhita, Molinaro, Annette M., Yang, Xiaodong, Kolkowitz, Ilan, Olow, Aleksandra, Wehmeijer, Noor, Orbach, Sharon, Chen, Justin, Matthay, Katherine K., Haas-Kogan, Daphne A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684561/
https://ncbi.nlm.nih.gov/pubmed/23482742
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