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Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site

BACKGROUND: Glutaminyl cyclase (QC) forms the pyroglutamyl residue at the amino terminus of numerous secretory peptides and proteins. We previously proposed the mammalian QC has some features in common with zinc aminopeptidases. We now have generated a structural model for human QC based on the amin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Booth, Rachell E, Lovell, Simon C, Misquitta, Stephanie A, Bateman, Robert C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC368447/
https://ncbi.nlm.nih.gov/pubmed/15028118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-2-2
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