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Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site
BACKGROUND: Glutaminyl cyclase (QC) forms the pyroglutamyl residue at the amino terminus of numerous secretory peptides and proteins. We previously proposed the mammalian QC has some features in common with zinc aminopeptidases. We now have generated a structural model for human QC based on the amin...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC368447/ https://ncbi.nlm.nih.gov/pubmed/15028118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-2-2 |
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