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Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site

BACKGROUND: Glutaminyl cyclase (QC) forms the pyroglutamyl residue at the amino terminus of numerous secretory peptides and proteins. We previously proposed the mammalian QC has some features in common with zinc aminopeptidases. We now have generated a structural model for human QC based on the amin...

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Detaylı Bibliyografya
Asıl Yazarlar: Booth, Rachell E, Lovell, Simon C, Misquitta, Stephanie A, Bateman, Robert C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC368447/
https://ncbi.nlm.nih.gov/pubmed/15028118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-2-2
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