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The serum- and glucocorticoid- induced protein kinase-1 (Sgk-1) mitochondria connection: Identification of the IF-1 inhibitor of the F(1)F(0)-ATPase as a mitochondria-specific binding target and the stress-induced mitochondrial localization of endogenous Sgk-1

The expression, localization and activity of the serum- and glucocorticoid- induced protein kinase, Sgk-1, are regulated by multiple hormonal and environmental cues including cellular stress. Biochemical fractionation and indirect immunofluorescence demonstrated that sorbitol induced hyperosmotic st...

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Detalhes bibliográficos
Main Authors: O’Keeffe, Bridget A., Cilia, Salvatore, Maiyar, Anita C., Vaysberg, Maria, Firestone, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684451/
https://ncbi.nlm.nih.gov/pubmed/23402912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2013.01.019
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