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Importin-α Mediates the Regulated Nuclear Targeting of Serum- and Glucocorticoid-inducible Protein Kinase (Sgk) by Recognition of a Nuclear Localization Signal in the Kinase Central Domain

The transcriptionally regulated serum and glucocorticoid inducible protein kinase (Sgk) is localized to the nucleus in a serum-dependent manner, and a yeast two-hybrid genetic screen uncovered a specific interaction between Sgk and the importin-α nuclear import receptor. In vitro GST pull down assay...

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Detalhes bibliográficos
Main Authors: Maiyar, Anita C., Leong, Meredith L.L., Firestone, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151592/
https://ncbi.nlm.nih.gov/pubmed/12631736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-03-0170
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