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Importin-α Mediates the Regulated Nuclear Targeting of Serum- and Glucocorticoid-inducible Protein Kinase (Sgk) by Recognition of a Nuclear Localization Signal in the Kinase Central Domain
The transcriptionally regulated serum and glucocorticoid inducible protein kinase (Sgk) is localized to the nucleus in a serum-dependent manner, and a yeast two-hybrid genetic screen uncovered a specific interaction between Sgk and the importin-α nuclear import receptor. In vitro GST pull down assay...
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Main Authors: | , , |
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格式: | Artigo |
語言: | Inglês |
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The American Society for Cell Biology
2003
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151592/ https://ncbi.nlm.nih.gov/pubmed/12631736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-03-0170 |
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