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IRE1, a double-edged sword in pre-miRNA slicing and cell death
IRE1α, the most conserved transducer of the unfolded protein response, plays critical roles in many biological processes and cell fate decisions. Reporting in Science, Upton et al. (2012) broadened our understanding of IRE1a as a cell-death executioner, showing that upon ER stress, IRE1α degrades mi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684431/ https://ncbi.nlm.nih.gov/pubmed/23153490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.10.025 |
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