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Life and death within germinal centres: a double-edged sword
Within germinal centres, B lymphocytes are destined to die by apoptosis via Fas signalling, unless they are positively rescued by antigen and by signals initiated by CD40–CD154 interactions. Thus, while the germinal centre microenvironment can become a virtual graveyard for most B lymphocytes that f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782796/ https://ncbi.nlm.nih.gov/pubmed/12383195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01494.x |
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