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LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker
There is a pressing need to identify prognostic markers of metastatic disease and targets for treatment. Combining high-throughput RNA sequencing, functional characterization, mechanistic studies and clinical validation, we identify leukemia inhibitory factor receptor (LIFR) as a breast cancer metas...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684419/ https://ncbi.nlm.nih.gov/pubmed/23001183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2940 |
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