Secretory Leukocyte Protease Inhibitor Reverses Inhibition by CNS Myelin, Promotes Regeneration in the Optic Nerve, and Suppresses Expression of the Transforming Growth Factor-β Signaling Protein Smad2

After CNS injury, axonal regeneration is limited by myelin-associated inhibitors; however, this can be overcome through elevation of intracellular cyclic AMP (cAMP), as occurs with conditioning lesions of the sciatic nerve. This study reports that expression of secretory leukocyte protease inhibitor...

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Main Authors: Hannila, Sari S., Siddiq, Mustafa M., Carmel, Jason B., Hou, Jianwei, Chaudhry, Nagarathnamma, Bradley, Peter M. J., Hilaire, Melissa, Richman, Erica L., Hart, Ronald P., Filbin, Marie T.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2013
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684282/
https://ncbi.nlm.nih.gov/pubmed/23516280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5321-12.2013
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