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Myelin-associated glycoprotein inhibits neurite outgrowth through inactivation of the small GTPase Rap1

Rap1 is a small GTPase that has been implicated in dendritic development and plasticity. In this study, we investigated the role of Rap1 in axonal growth and its activation in response to neurotrophins and myelin-associated inhibitors. We report that Rap1 is activated by brain-derived neurotrophic f...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Nikulina, Elena, Gkioka, Vasiliki, Siddiq, Mustafa M., Mellado, Wilfredo, Hilaire, Melissa, Cain, Christine R., Hannila, Sari S., Filbin, Marie T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217748/
https://ncbi.nlm.nih.gov/pubmed/31985825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13740
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