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Myelin-associated glycoprotein inhibits neurite outgrowth through inactivation of the small GTPase Rap1

Rap1 is a small GTPase that has been implicated in dendritic development and plasticity. In this study, we investigated the role of Rap1 in axonal growth and its activation in response to neurotrophins and myelin-associated inhibitors. We report that Rap1 is activated by brain-derived neurotrophic f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FEBS Lett
Prif Awduron: Nikulina, Elena, Gkioka, Vasiliki, Siddiq, Mustafa M., Mellado, Wilfredo, Hilaire, Melissa, Cain, Christine R., Hannila, Sari S., Filbin, Marie T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7217748/
https://ncbi.nlm.nih.gov/pubmed/31985825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13740
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