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Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats

BACKGROUND: Clinical and animal data indicate that gut-derived endotoxin and other luminal bacterial products are necessary cofactors for development of alcoholic liver disease (ALD). Although gut leakiness is clearly an important cause of endotoxemia in ALD, it cannot fully explain endotoxemia in a...

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Autors principals: Mutlu, Ece, Keshavarzian, Ali, Engen, Phillip, Forsyth, Christopher B., Sikaroodi, Masoumeh, Gillevet, Patrick
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684271/
https://ncbi.nlm.nih.gov/pubmed/19645728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2009.01022.x
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