Exploratory, anxiety and spatial memory impairments are dissociated in mice lacking the LPA(1) receptor

Lysophosphatidic acid (LPA) is a new, intercellular signalling molecule in the brain that has an important role in adult hippocampal plasticity. Mice lacking the LPA(1) receptor exhibit motor, emotional and cognitive alterations. However, the potential relationship among these concomitant impairment...

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Main Authors: Castilla-Ortega, Estela, Sánchez-López, Jorge, Hoyo-Becerra, Carolina, Matas-Rico, Elisa, Zambrana-Infantes, Emma, Chun, Jerold, Fonseca, Fernando Rodríguez De, Pedraza, Carmen, Estivill-Torrús, Guillermo, Santin, Luis J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684252/
https://ncbi.nlm.nih.gov/pubmed/20388543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2010.04.003
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