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CYTOKINE-INDUCED CHROMATIN MODIFICATIONS OF THE TYPE I COLLAGEN ALPHA 2 GENE DURING INTESTINAL ENDOTHELIAL-TO-MESENCHYMAL TRANSITION

BACKGROUND: Fibrosis of the intestine is currently an irreversible complication of Inflammatory Bowel Disease yet little is understood of the underlying pathogenesis and anti-fibrotic strategies remain elusive. To develop effective therapies, knowledge of the mechanism of transcription and excessive...

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Detalhes bibliográficos
Main Authors: Sadler, Tammy, Scarpa, Melania, Rieder, Florian, West, Gail, Stylianou, Eleni
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684204/
https://ncbi.nlm.nih.gov/pubmed/23635716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e318281f37a
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