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Selective TRIF-Dependent Signaling by a Synthetic Toll-Like Receptor 4 Agonist
In response to ligand binding to the Toll-like receptor 4 (TLR4) and myeloid differentiation-2 (MD-2) receptor complex, two major signaling pathways are activated that involve different adaptor proteins. One pathway depends on myeloid differentiation marker 88 (MyD88), which elicits proinflammatory...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684200/ https://ncbi.nlm.nih.gov/pubmed/22337809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001963 |
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