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Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi
Endogenous RNA interference (endo-RNAi) pathways employ a variety of mechanisms to generate short-interfering (si) RNAs and to mediate gene silencing. In Caenorhabditis elegans, DCR-1 is essential for competing RNAi pathways - the ERI endo-RNAi pathway and the exogenous RNAi pathway. Here, we demons...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684169/ https://ncbi.nlm.nih.gov/pubmed/22179787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2186 |
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