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MicroRNA-1291-mediated silencing of IRE1α enhances Glypican-3 expression

MicroRNAs (miRNA) are generally described as negative regulators of gene expression. However, some evidence suggests that they may also play positive roles. As such, we reported that miR-1291 leads to a GPC3 mRNA expression increase in hepatoma cells through a 3′ untranslated region (UTR)-dependent...

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Hlavní autoři: Maurel, Marion, Dejeans, Nicolas, Taouji, Saïd, Chevet, Eric, Grosset, Christophe F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683912/
https://ncbi.nlm.nih.gov/pubmed/23598528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.036483.112
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