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Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs

Due to structural flexibility, RNase sensitivity, and serum instability, RNA nanoparticles with concrete shapes for in vivo application remain challenging to construct. Here we report the construction of 14 RNA nanoparticles with solid shapes for targeting cancers specifically. These RNA nanoparticl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shu, Yi, Haque, Farzin, Shu, Dan, Li, Wei, Zhu, Zhenqi, Kotb, Malak, Lyubchenko, Yuri, Guo, Peixuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683911/
https://ncbi.nlm.nih.gov/pubmed/23604636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.037002.112
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