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The Role of Prolactin Receptor in GH Signaling in Breast Cancer Cells

GH and prolactin (PRL) are structurally related hormones that exert important effects in disparate target tissues. Their receptors (GHR and PRLR) reside in the cytokine receptor superfamily and share signaling pathways. In humans, GH binds both GHR and PRLR, whereas PRL binds only PRLR. Both hormone...

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Autori principali: Xu, Jie, Sun, Dongmei, Jiang, Jing, Deng, Luqin, Zhang, Yue, Yu, Hao, Bahl, Deepti, Langenheim, John F., Chen, Wen Y., Fuchs, Serge Y., Frank, Stuart J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683809/
https://ncbi.nlm.nih.gov/pubmed/23192981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1297
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