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Viral genome structures are optimal for capsid assembly

Understanding how virus capsids assemble around their nucleic acid (NA) genomes could promote efforts to block viral propagation or to reengineer capsids for gene therapy applications. We develop a coarse-grained model of capsid proteins and NAs with which we investigate assembly dynamics and thermo...

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Detalhes bibliográficos
Main Authors: Perlmutter, Jason D, Qiao, Cong, Hagan, Michael F
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683802/
https://ncbi.nlm.nih.gov/pubmed/23795290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00632
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