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Viral genome structures are optimal for capsid assembly

Understanding how virus capsids assemble around their nucleic acid (NA) genomes could promote efforts to block viral propagation or to reengineer capsids for gene therapy applications. We develop a coarse-grained model of capsid proteins and NAs with which we investigate assembly dynamics and thermo...

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Bibliografiske detaljer
Main Authors: Perlmutter, Jason D, Qiao, Cong, Hagan, Michael F
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683802/
https://ncbi.nlm.nih.gov/pubmed/23795290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00632
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