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Antibody-based therapy of acute myeloid leukemia with gemtuzumab ozogamicin

Antibodies have created high expectations for effective yet tolerated therapeutics in acute myeloid leukemia (AML). Hitherto the most exploited target is CD33, a myeloid differentiation antigen found on AML blasts in most patients and, perhaps, leukemic stem cells in some. Treatment efforts have foc...

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Bibliographic Details
Main Authors: Cowan, Andrew J., Laszlo, George S., Estey, Elihu H., Walter, Roland B.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683663/
https://ncbi.nlm.nih.gov/pubmed/23747885
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