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Torsin mediates primary envelopment of large ribonucleoprotein granules at the nuclear envelope

A previously unrecognized mechanism by which large ribonucleoprotein (megaRNP) granules exit the nucleus is by budding through the nuclear envelope (NE). This mechanism is akin to the nuclear egress of Herpes-type viruses and is essential for proper synapse development. However, the molecular machin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jokhi, Vahbiz, Ashley, James, Noma, Akiko, Ito, Naoto, Wakabayashi-Ito, Noriko, Moore, Melissa J., Budnik, Vivian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683601/
https://ncbi.nlm.nih.gov/pubmed/23583177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.03.015
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