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Engineering Lactococcus lactis for Production of Mannitol: High Yields from Food-Grade Strains Deficient in Lactate Dehydrogenase and the Mannitol Transport System

Mannitol is a sugar polyol claimed to have health-promoting properties. A mannitol-producing strain of Lactococcus lactis was obtained by disruption of two genes of the phosphoenolpyruvate (PEP)-mannitol phosphotransferase system (PTS(Mtl)). Genes mtlA and mtlF were independently deleted by double-c...

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Detalhes bibliográficos
Main Authors: Gaspar, Paula, Neves, Ana Rute, Ramos, Ana, Gasson, Michael J., Shearman, Claire A., Santos, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC368346/
https://ncbi.nlm.nih.gov/pubmed/15006767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.3.1466-1474.2004
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