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High Yields of 2,3-Butanediol and Mannitol in Lactococcus lactis through Engineering of NAD(+) Cofactor Recycling

Manipulation of NADH-dependent steps, and particularly disruption of the las-located lactate dehydrogenase (ldh) gene in Lactococcus lactis, is common to engineering strategies envisaging the accumulation of reduced end products other than lactate. Reverse transcription-PCR experiments revealed that...

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Detalhes bibliográficos
Main Authors: Gaspar, Paula, Neves, Ana Rute, Gasson, Michael J., Shearman, Claire A., Santos, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187077/
https://ncbi.nlm.nih.gov/pubmed/21841021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.05544-11
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