Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)

BACKGROUND: Plasmodium falciparum circumsporozoite protein (CSP) is a leading malaria vaccine candidate antigen, known to elicit protective antibody responses in humans (RTS,S vaccine). Recently, a DNA prime / adenovirus (Ad) vector boost vaccine encoding CSP and a second P. falciparum antigen, apic...

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Hlavní autoři: Sedegah, Martha, Kim, Yohan, Ganeshan, Harini, Huang, Jun, Belmonte, Maria, Abot, Esteban, Banania, Jo Glenna, Farooq, Fouzia, McGrath, Shannon, Peters, Bjoern, Sette, Alessandro, Soisson, Lorraine, Diggs, Carter, Doolan, Denise L, Tamminga, Cindy, Villasante, Eileen, Hollingdale, Michael R, Richie, Thomas L
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683343/
https://ncbi.nlm.nih.gov/pubmed/23738590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-185
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