Differential loss of invariant NKT cells and FoxP3+ regulatory T cells in HIV-1 subtype A and subtype D infections

HIV-1 subtype D is associated with faster disease progression as compared to subtype A. Immunological correlates of this difference remain undefined. We investigated invariant natural killer T cells and FoxP3+ regulatory T cells in Ugandans infected with either subtype. Loss of iNKT cells was pronou...

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Hauptverfasser: Flach, Britta, Naluyima, Prossy, Blom, Kim, Gonzalez, Veronica D., Eller, Leigh Anne, Laeyendecker, Oliver, Quinn, Thomas C., Serwadda, David, Sewankambo, Nelson K., Wawer, Maria J., Gray, Ronald H., Michael, Nelson L., Wabwire-Mangen, Fred, Robb, Merlin L., Eller, Michael A., Sandberg, Johan K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683089/
https://ncbi.nlm.nih.gov/pubmed/23403863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31828b2073
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