Probucol Increases Striatal Glutathione Peroxidase Activity and Protects against 3-Nitropropionic Acid-Induced Pro-Oxidative Damage in Rats

Huntington’s disease (HD) is an autosomal dominantly inherited neurodegenerative disease characterized by symptoms attributable to the death of striatal and cortical neurons. The molecular mechanisms mediating neuronal death in HD involve oxidative stress and mitochondrial dysfunction. Administratio...

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Main Authors: Colle, Dirleise, Santos, Danúbia Bonfanti, Moreira, Eduardo Luiz Gasnhar, Hartwig, Juliana Montagna, dos Santos, Alessandra Antunes, Zimmermann, Luciana Teixeira, Hort, Mariana Appel, Farina, Marcelo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683065/
https://ncbi.nlm.nih.gov/pubmed/23799154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067658
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