Probucol Increases Striatal Glutathione Peroxidase Activity and Protects against 3-Nitropropionic Acid-Induced Pro-Oxidative Damage in Rats

Huntington’s disease (HD) is an autosomal dominantly inherited neurodegenerative disease characterized by symptoms attributable to the death of striatal and cortical neurons. The molecular mechanisms mediating neuronal death in HD involve oxidative stress and mitochondrial dysfunction. Administratio...

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Bibliographic Details
Main Authors: Colle, Dirleise, Santos, Danúbia Bonfanti, Moreira, Eduardo Luiz Gasnhar, Hartwig, Juliana Montagna, dos Santos, Alessandra Antunes, Zimmermann, Luciana Teixeira, Hort, Mariana Appel, Farina, Marcelo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683065/
https://ncbi.nlm.nih.gov/pubmed/23799154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067658
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