Uptake and Intracellular Trafficking of Superantigens in Dendritic Cells

Bacterial superantigens (SAgs) are exotoxins produced mainly by Staphylococcus aureus and Streptococcus pyogenes that can cause toxic shock syndrome (TSS). According to current paradigm, SAgs interact directly and simultaneously with T cell receptor (TCR) on the T cell and MHC class II (MHC-II) on t...

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Autori principali: Ganem, María B., De Marzi, Mauricio C., Fernández-Lynch, María J., Jancic, Carolina, Vermeulen, Mónica, Geffner, Jorge, Mariuzza, Roy A., Fernández, Marisa M., Malchiodi, Emilio L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682983/
https://ncbi.nlm.nih.gov/pubmed/23799083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066244
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