Systemic Administration of Abeta mAb Reduces Retinal Deposition of Abeta and Activated Complement C3 in Age-Related Macular Degeneration Mouse Model

Age-related macular degeneration (AMD) is a leading cause of legal blindness in the Western world. There are effective treatments for the vascular complications of neo-vascular AMD, but no effective therapies are available for the dry/atrophic form of the disease. A previously described transgenic C...

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Bibliografische gegevens
Hoofdauteurs: Catchpole, Ian, Germaschewski, Volker, Hoh Kam, Jaimie, Lundh von Leithner, Peter, Ford, Susannah, Gough, Gerald, Adamson, Peter, Overend, Philip, Hilpert, Jan, López, Francisco J., Ng, Yin Shan Eric, Coffey, Pete, Jeffery, Glen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682980/
https://ncbi.nlm.nih.gov/pubmed/23799019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065518
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