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Levels of (S)-N′-Nitrosonornicotine in U.S. Tobacco Products

INTRODUCTION: N′-nitrosonornicotine (NNN), an esophageal and oral carcinogen present in tobacco products, has a chiral center in its structure. Of its two enantiomers, (S)-NNN exhibits higher tumorigenic potency than (R)-NNN. There is no information available on the levels of (S)-NNN in various toba...

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Autors principals: Stepanov, Irina, Yershova, Katrina, Carmella, Steven, Upadhyaya, Pramod, Hecht, Stephen S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682840/
https://ncbi.nlm.nih.gov/pubmed/23212437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/nts249
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