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Impact of chronic congestive heart failure on pharmacokinetics and vasomotor effects of infused nitrite

BACKGROUND AND PURPOSE: Nitrite (NO(2)(−)) has recently been shown to represent a potential source of NO, in particular under hypoxic conditions. The aim of the current study was to compare the haemodynamic effects of NO(2)(−) in healthy volunteers and patients with stable congestive heart failure (...

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Autori principali: Maher, Abdul R, Arif, Sayqa, Madhani, Melanie, Abozguia, Khalid, Ahmed, Ibrar, Fernandez, Bernadette O, Feelisch, Martin, O'Sullivan, AG, Christopoulos, Arthur, Sverdlov, Aaron L, Ngo, Doan, Dautov, Rustem, James, Philip E, Horowitz, John D, Frenneaux, Michael P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682712/
https://ncbi.nlm.nih.gov/pubmed/23472879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12152
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