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Kallikrein-related Peptidase 5 Functions in Proteolytic Processing of Profilaggrin in Cultured Human Keratinocytes

Filaggrin protein is synthesized in the stratum granulosum of the skin and contributes to the formation of the human skin barrier. Profilaggrin is cleaved by proteolytic enzymes and converted to functional filaggrin, but its processing mechanism remains not fully elucidated. Kallikrein-related pepti...

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Detalles Bibliográficos
Main Authors: Sakabe, Jun-ichi, Yamamoto, Mami, Hirakawa, Satoshi, Motoyama, Akira, Ohta, Isao, Tatsuno, Kazuki, Ito, Taisuke, Kabashima, Kenji, Hibino, Toshihiko, Tokura, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682523/
https://ncbi.nlm.nih.gov/pubmed/23629652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476820
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