Kallikrein-related Peptidase 5 Functions in Proteolytic Processing of Profilaggrin in Cultured Human Keratinocytes

Filaggrin protein is synthesized in the stratum granulosum of the skin and contributes to the formation of the human skin barrier. Profilaggrin is cleaved by proteolytic enzymes and converted to functional filaggrin, but its processing mechanism remains not fully elucidated. Kallikrein-related pepti...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Sakabe, Jun-ichi, Yamamoto, Mami, Hirakawa, Satoshi, Motoyama, Akira, Ohta, Isao, Tatsuno, Kazuki, Ito, Taisuke, Kabashima, Kenji, Hibino, Toshihiko, Tokura, Yoshiki
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
נושאים:
Protein Synthesis and Degradation
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682523/
https://ncbi.nlm.nih.gov/pubmed/23629652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476820
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