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JosD1, a Membrane-targeted Deubiquitinating Enzyme, Is Activated by Ubiquitination and Regulates Membrane Dynamics, Cell Motility, and Endocytosis

The functional diversity of deubiquitinating enzymes (DUBs) is not well understood. The MJD family of DUBs consists of four cysteine proteases that share a catalytic “Josephin” domain. The family is named after the DUB ATXN3, which causes the neurodegenerative disease Machado-Joseph disease. The two...

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Bibliographische Detailangaben
Hauptverfasser: Seki, Takahiro, Gong, Lijie, Williams, Aislinn J., Sakai, Norio, Todi, Sokol V., Paulson, Henry L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682520/
https://ncbi.nlm.nih.gov/pubmed/23625928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.463406
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