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HER2-specific T cells target primary Glioblastoma stem cells and induce regression of autologous experimental tumors

PURPOSE: Glioblastoma (GBM) is the most aggressive human primary brain tumor and is currently incurable. Immunotherapies have the potential to target GBM stem cells, which are resistant to conventional therapies. Human epidermal growth factor receptor 2 (HER2) is a validated immunotherapy target and...

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Detalhes bibliográficos
Main Authors: Ahmed, Nabil, Salsman, Vita S, Kew, Yvonne, Shaffer, Donald, Powell, Suzanne, Zhang, Yi J, Grossman, Robert G, Heslop, Helen E, Gottschalk, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682507/
https://ncbi.nlm.nih.gov/pubmed/20068073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1322
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