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Characterizing the Membrane-Bound State of Cytochrome P450 3A4: Structure, Depth of Insertion, and Orientation
[Image: see text] Cytochrome P450 3A4 (CYP3A4) is the most abundant membrane-associated isoform of the P450 family in humans and is responsible for biotransformation of more than 50% of drugs metabolized in the body. Despite the large number of crystallographic structures available for CYP3A4, no st...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Chemical Society
2013
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682445/ https://ncbi.nlm.nih.gov/pubmed/23697766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4003525 |
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