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Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy
Malignant cells may evade death from cytotoxic agents if they are in a dormant state. The host microenvironment plays important roles in cancer progression, but how niches might control cancer cell dormancy is little understood. Here we show that osteopontin (OPN), an extracellular matrix molecule s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682335/ https://ncbi.nlm.nih.gov/pubmed/23589674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-475483 |
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