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Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair

mRNAs can be targeted to specific neuronal subcellular domains, which enables rapid changes in the local proteome through local translation. This mRNA-based mechanism links extrinsic signals to spatially restricted cellular responses and can mediate stimulus-driven adaptive responses such as dendrit...

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Detalhes bibliográficos
Main Authors: Jung, Hosung, Yoon, Byung C., Holt, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682205/
https://ncbi.nlm.nih.gov/pubmed/22498899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3210
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