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Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair
mRNAs can be targeted to specific neuronal subcellular domains, which enables rapid changes in the local proteome through local translation. This mRNA-based mechanism links extrinsic signals to spatially restricted cellular responses and can mediate stimulus-driven adaptive responses such as dendrit...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682205/ https://ncbi.nlm.nih.gov/pubmed/22498899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3210 |
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