Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs

Polycomb repressor complexes (PRCs) are important chromatin modifiers fundamentally implicated in pluripotency and cancer. Polycomb silencing in embryonic stem cells (ESCs) can be accompanied by active chromatin and primed RNA polymerase II (RNAPII), but the relationship between PRCs and RNAPII rema...

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Main Authors: Brookes, Emily, de Santiago, Inês, Hebenstreit, Daniel, Morris, Kelly J., Carroll, Tom, Xie, Sheila Q., Stock, Julie K., Heidemann, Martin, Eick, Dirk, Nozaki, Naohito, Kimura, Hiroshi, Ragoussis, Jiannis, Teichmann, Sarah A., Pombo, Ana
格式: Artigo
語言:Inglês
出版: Cell Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682187/
https://ncbi.nlm.nih.gov/pubmed/22305566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.12.017
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