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Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs
Polycomb repressor complexes (PRCs) are important chromatin modifiers fundamentally implicated in pluripotency and cancer. Polycomb silencing in embryonic stem cells (ESCs) can be accompanied by active chromatin and primed RNA polymerase II (RNAPII), but the relationship between PRCs and RNAPII rema...
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
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Cell Press
2012
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3682187/ https://ncbi.nlm.nih.gov/pubmed/22305566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.12.017 |
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