Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs

Polycomb repressor complexes (PRCs) are important chromatin modifiers fundamentally implicated in pluripotency and cancer. Polycomb silencing in embryonic stem cells (ESCs) can be accompanied by active chromatin and primed RNA polymerase II (RNAPII), but the relationship between PRCs and RNAPII rema...

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Autors principals: Brookes, Emily, de Santiago, Inês, Hebenstreit, Daniel, Morris, Kelly J., Carroll, Tom, Xie, Sheila Q., Stock, Julie K., Heidemann, Martin, Eick, Dirk, Nozaki, Naohito, Kimura, Hiroshi, Ragoussis, Jiannis, Teichmann, Sarah A., Pombo, Ana
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682187/
https://ncbi.nlm.nih.gov/pubmed/22305566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.12.017
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